You take the Southern Iteramerican Road (towards the South-Panama, you have to pass by Cartago) and start going up until you reach the km # 80 (there are Yellow Markers called “Mojones” that have the #km.).
You have to pass by a famous restaurant called “Chespiritos # 3” witch is right in front of the “Los Quetzales National Park” before reaching the Km.#.80. and then you will see a sign with “San Gerardo” on it, right beside other signs form other Lodges, among them “El Manantial” Logo.
Take a right and start going down about 9 km. (in a semi-paved road) you should see the Lodge sign after about 6 km and then go on for tree more. El Manantial is 9 km away from the Interamerican Road, on your right side (if you reach a little church and school you passed by 200 m.)